We have been busy publishing new articles!
More evidence that increased stiffness of the large arteries (as occurs in old age) can lead to poor outcomes for the blood vessels in the brain: https://physoc.onlinelibrary.wiley.com/doi/10.1113/EP087453
Atherosclerosis is more likely to develop in locations where blood flow is disturbed, like artery branches or curves. We find that a Western Diet, high in fat and sucrose, increases the atherosclerosis response to disturbed blood flow. However, contrary to our hypothesis, aging did not change the response: https://rdcu.be/boDWR
Telomeres, the ends of chromosomes, form a protective loop called a “cap.” We provide cause-and-effect evidence that removing this cap leads to artery dysfunction, similar to aging: https://www.sciencedirect.com/science/article/pii/S002228281830751X
We find that increasing angiogenesis and/or altering vascular stability protects against metabolic dysfunction with a high fat diet: https://onlinelibrary.wiley.com/doi/abs/10.1111/micc.12540